Concerted Genetic Function in Blood Traits.

TitleConcerted Genetic Function in Blood Traits.
Publication TypeJournal Article
Year of Publication2016
AuthorsKim-Hellmuth, S, Lappalainen, T
JournalCell
Volume167
Issue5
Pagination1167-1169
Date Published2016 11 17
ISSN1097-4172
KeywordsGenetic Predisposition to Disease, Genetic Variation, Genome-Wide Association Study, Humans, Phenotype, Polymorphism, Single Nucleotide
Abstract

The hematopoietic system plays a major role in human health. Two studies by Astle et al. and Chen et al. published in this issue of Cell use genome-wide association and functional genomics approaches to provide deep insights into the role of genetic variants in hematological traits. We discuss these discoveries and future strategies toward completing our understanding of the genetic basis for variation in human traits.

DOI10.1016/j.cell.2016.10.055
Alternate JournalCell
PubMed ID27863238
Grant ListR01 MH106842 / MH / NIMH NIH HHS / United States
UM1 HG008901 / HG / NHGRI NIH HHS / United States